Manchester City host Tottenham Hotspur on Saturday on the back of a record 15 successive English Premier League wins, and on the basis of their visitors' recent away form, a 16th victory appears to be the likely outcome.
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
Only one point separates the two sides with Chelsea on 31 and City on 30 but Antonio Conte's impact at Stamford Bridge appears greater than his City counterpart Pep Guardiola's at the Etihad.
IMAGES from Saturday's English Premier League matches.
Top-class goals from Bernardo Silva and Sergio Aguero took Manchester City back to the top of the Premier League in a 2-0 win over Fulham at Craven Cottage on Saturday.
Manchester United, buoyed by five successive Premier League victories, head into Sunday's derby against Manchester City a place and a point above their rivals and believing they are poised to restore red ascendancy in the city.
For the second time in a week Manchester City threw away a 2-0 lead against a Premier League struggler but this time they hit back as Frank Lampard came off the bench to secure a 3-2 win over Sunderland on Thursday.
Arsenal shoved Chelsea off the top of the table but Leicester City's Jamie Vardy, with a dazzling hat-trick, was the man of the moment on Saturday as the struggling Premier League champions blew aside Manchester City 4-2.
Sergio Aguero scored five times in 20 minutes including an eight-minute hat-trick as Manchester City came from behind to thrash Newcastle United 6-1 and go back to the top of the Premier League table on Saturday.
Chelsea have topped the spending list with Manchester United not far behind, but West Ham United's business epitomises the TV riches which give all Premier League clubs spending power that only the elite teams in Spain or Germany can dream of.
Leeds sack Gracia, Allardyce to step in till season ends
Chelsea landed a potentially decisive blow in the Premier League title race with a 2-1 win at Aston Villa on Saturday that put them seven points clear of Manchester City, who self-destructed in a 1-1 draw at home to Hull.
Robert Huth's double and a Riyad Mahrez goal sent Premier League leaders Leicester City six points clear after a stunning 3-1 victory at shell-shocked title rivals Manchester City on Saturday.
Images from the English Premier League matches played on Saturday
Images from the English Premier League matches played on Saturday.
Chelsea found no chink in Everton's defensive armour as the Premier League champions were held to a frustrating 0-0 draw at Goodison Park on Saturday.
A summary of Sunday's Premier League matches
Images from the EPL matches played on Saturday
Chelsea ripped apart Premier League title rivals Arsenal in a 6-0 mauling at Stamford Bridge on Saturday to ensure Arsene Wenger's 1,000th game turned sour and Liverpool and Manchester City kept up the pressure with big wins.
City have 89 points, one more than rivals Liverpool, with both teams having three games to play -- and none of them against top six opponents.
News of all that's transpired on and off the football field.
On a day of frenetic spending that took the Premier League total to a record far above one billion pounds ($1.29 billion), Antonio Conte's side also missed out on two of their other targets - Alex Oxlade-Chamberlain and Fernando Llorente.
Chelsea will look to make amends after being runners-up to Leicester City and Arsenal in the last two seasons
Leicester City were give a Premier League reality check when the unlikely leaders lost 1-0 at Liverpool on Saturday after Manchester United slumped to a third consecutive league defeat to pile more pressure on manager Louis van Gaal.
The Premier League season is only a week old and the problems are already piling up for misfiring champions Chelsea after a 3-0 thrashing at Manchester City on Sunday.
IMAGES from the Premier League matches played on Sunday.
Records fell on the final day of the Premier League season on Sunday as Manchester City beat Southampton 1-0 to become the first team to reach 100 points and Mohamed Salah established a new Premier League goalscoring mark as Liverpool clinched a top-four spot.
Late goals from Nicklas Bendtner and Theo Walcott spared Arsenal's blushes and kept them top of the Premier League in a 2-0 victory over Cardiff City as title rivals Manchester City and Chelsea also won on Wednesday.
Liverpool forward Sadio Mane scored his 100th goal for the club to help secure a 3-0 victory over lively Crystal Palace in the Premier League at Anfield on Saturday.
Manchester City embark on a fifth Champions League campaign buoyant after a perfect start to their domestic season but still searching for the secret formula against Europe's top brass.
Images from Tuesday's action in the Premier League
Manchester City failed in an audacious transfer deadline day move for Leicester City midfielder Riyadh Mahrez, British media reported on Wednesday.
Theo Walcott's double fired Arsenal back to the top of the Premier League as the Gunners got their title challenge back on track with a 3-1 victory at West Ham United on Thursday.
IMAGES from the English Premier League matches played on Saturday.
Leicester City's Premier League title defence got off to a terrible start as they were beaten 2-1 at promoted Hull City, who shrugged off an injury crisis to shock the champions on the opening day of the new season on Saturday
Liverpool will resume their quest for a first top-flight title in 30 years at city rivals Everton on June 21, as the English Premier League released its revised fixture list for the first three weeks of the restarted season on Friday. Liverpool are 25 points clear at the top and are two victories away from winning the Premier League, but will have a shot at securing the title by beating Everton if City lose to Arsenal.
It is a first win in six games in all competitions for Liverpool.
Raheem Sterling scored a hat-trick as champions Manchester City made a convincing start to their title defence with a 5-0 win over West Ham United.
A round-up of Saturday's matches in the English Premier League.
Chelsea and Manchester City tightened their stranglehold on the Premier League title race on Saturday, recording victories over struggling clubs to stretch further clear of their increasingly forlorn pursuers.
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